Correlation between autoimmune thyroid diseases and helicobacter pylori infection

Background: Helicobacter Pylori (H. Pylori) usually acquired in childhood, it colonizes the gastric mucosa of about 50% of the world's population at some time in their life. In eastern countries, H. pylori infection has a prevalence of approximately 70%. Objective: To correlate between H. pylori infection and autoimmune thyroid diseases (AITD). Patients and Methods: This is a cross-sectional study done on 200 patients selected as a convenient sample with upper GI upset. They were selected from gastroenterology outpatient clinics at Al-Hussein and Alexandria Police Hospitals, during the summer months of 2018. They were classified according to the results of stool H. pylori Ag testing into two groups; positive and negative (each group 100 patient). This is cross-sectional study done on 200 patients selected as a convenient sample Results: Our results indicated that patients with H. pylori infection were more susceptible to AITD. There was significant association between H. pylori infection and both Hashimoto's and Graves' disease. H. pylori infection had shown to be associated with elevated liver enzymes, anemia, and IL 17. Conclusion: There is a significant positive relationship between H. pylori infection and Hashimoto's disease (HT). There is a significant positive relationship between H. pylori infection and Graves' disease (GD)

Fonoresultados en paciente con reconstrucción inmediata del nervio laríngeo recurrente durante cirugía de tiroides / Vocal outcome after immediate reconstruction of the recurrent laryngeal nerve in thyroid surgery

Objetivo: Evaluar la función fonatoria de pacientes con reconstrucción inmediata del Nervio Laríngeo Recurrente durante cirugía de tiroides. Materiales y Métodos: Se incluyeron 10 pacientes con sección unilateral del Nervio Laríngeo Recurrente con reconstrucción inmediata durante cirugía de tiroides, por anastomosis directa. Se analizaron los registros video-estroboscópicos, índice de Discapacidad Vocal y análisis acústico de la voz post-operatorios. Diseño:Resultados: Seguimiento de 24,2 ±17.3 meses. Análisis acústico de la voz, con prolongación del Jitter (1.39 ± 0.99 DE) y un tiempo máximo fonatorio disminuido de 10.9 ± 3.07 segundos. Cierre glótico completo en el 90% de los casos. El valor promedio del Índice de Discapacidad Vocal fue leve (22.7 ± 11.8 DE). Conclusión: Los resultados anatómicos y funcionales demuestran que esta técnica quirúrgica preserva la función fonatoria y la soportan como manejo primario de este tipo de lesiones correlacionándose con resultados ya descritos en la literatura.

Objective: Assess the phonatory function of patients with immediate reconstruction of the recurrent laryngeal nerve during thyroid surgery. Materials and Methods: 10 patients with unilateral recurrent laryngeal nerve section, with immediate reconstruction performed during thyroid surgery by direct anastomosis. Postoperative stroboscopy records, Voice Handicap Index and acoustic voice analysis were recollected. Design: Results: Follow-up 24,2 ±17.3 months. Acoustic voice analysis, with prolonged Jitter (1.39 ± 0.99 DE) and maximum phonation time decreased of 10.9 ± 3.07 seconds. Complete glottal closure in 90% of cases. The average value of Voice Handicap Index was mild (22.7 ± 11.8 DE). Conclusion: Anatomical and functional results demonstrates immediate reinnervation preserves the phonatory function, and supports it, as a primary management of this type of injury, in correlation with results already described in the literature.